Legend Biotech Corporation American Depositary Shares 2026 Q2 Earnings Call
Review the key takeaways and the transcript of this earnings call.
- Legend Biotech reported strong second quarter 2026 performance with Carvykti global net trade sales of approximately $657 million, representing 50% year-over-year growth and 10% sequential growth from Q1 2026.
- In the U.S., Carvykti sales increased 32% year-over-year and 9% quarter-over-quarter, driven by accelerating adoption in earlier lines of therapy, now comprising over 70% of volume in second to fourth lines.
- Ex-U.S. sales grew 128% year-over-year, supported by expansion into 19 markets and 348 global treatment sites including a recent launch in Ireland.
- Adjusted net income was $63 million in Q2 2026, marking the first quarter of company-wide profitability on both IFRS and adjusted bases, with adjusted net income per diluted share of $0.16 compared to $0.03 in Q2 2025.
- Gross margin on net product sales improved to 58% in Q2 2026, up 17 percentage points from Q1 2026, with expectations of some quarter-to-quarter variability going forward.
- Total revenue increased 52% year-over-year, supported by Carvykti demand and commercial expansion.
- Operating expenses increased 7% year-over-year, with R&D expenses down 2% and SG&A expenses up 19%, reflecting investments to support market leadership.
- Cash, cash equivalents, and time deposits totaled approximately $965 million at the end of Q2 2026, with no long-term debt after loan repayments to Johnson & Johnson.
- Clinical updates included encouraging early human data from the phase 1b LP 2501 in vivo CAR-T study for relapsed/refractory non-Hodgkin's lymphoma, showing 100% objective response rate and 83.3% complete response rate at the higher dose cohort.
- Additional data from Carvykti clinical programs demonstrated durable efficacy and consistent safety across cytogenetic risk groups in multiple myeloma.
- Legend Biotech completed a $212 million net proceeds public equity offering to fund pipeline development and repay debt.
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Transcript
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Good day everyone, and thank you for standing by. Welcome to Legend Biotech second quarter 2026 earnings call. At this time, all participants are in a listen-only mode. After the speakers' presentation, there will be a question and answer session. To ask a question, you will need to press star one one on your telephone. You will then hear a message advising your hand is raised. To withdraw your question, please press star one one again. Please be advised that today's conference is being recorded. Now it's my pleasure to hand the conference to Caroline Paul, Director of Investor Relations. Please go ahead. Good morning.
This is Caroline Paul, Director of Investor Relations at Legend Biotech. Thank you for joining our conference call today to review our second quarter 2026 performance. Prior to this call, we issued a press release announcing our financial results for the quarter, which can be found on the Legend Biotech Investor Relations website. Joining me on today's call are Alan Bash, the company's Interim Chief Executive Officer, and Carlos Santos, the company's Chief Financial Officer. Following the prepared remarks, we will open up the call for Q&A. We also have our Interim Head of R&D, Yuhong Qiu, joining the Q&A session. During today's call, we will be making forward-looking statements which are subject to risks and uncertainties that may cause our actual results to differ materially from those expressed or implied herewith it.
These forward-looking statements are discussed in greater detail in our SEC filings, which we encourage you to read and can be found under the Investors section of our company website. In addition, adjusted net income or loss is a non-IFRS metric. This non-IFRS financial measure is an addition to and not a substitute for or superior to measures of financial performance prepared in accordance with IFRS. There are a number of limitations related to the use of these non-IFRS financial measures versus their closest IFRS equivalents. However, we believe that providing information concerning adjusted net income or loss and adjusted net income or loss per share enhances an investor's understanding of our financial performance. Our press release includes IFRS to non-IFRS reconciliations for these measures. With that, I will now turn the call over to Alan.
Thank you Caroline, and good morning everyone. I want to start by briefly addressing the leadership transition announced last month. As you all know, Dr. Ying Huang stepped down as Chief Executive Officer and member of the board, and the board appointed me to serve as Interim Chief Executive Officer. On behalf of the board and all our employees, I want to thank Ying for his leadership over many years and his many contributions to Legend Biotech. We want to be very clear, this is a leadership transition, not a strategy transition. Our priorities remain unchanged. We remain focused on three main objectives: maximizing CARVYKTI, advancing our next generation pipeline, and strengthening our execution on all fronts. My commitment is to provide continuity, transparency, and disciplined execution, working closely with Carlos, our senior R&D team, the board, and the broader leadership team to maintain momentum across the business.
We are operating from a strong foundation with continued CARVYKTI momentum, meaningful progress across our in vivo CAR-T platform, and as you are about to see from the Q2 results, the financial flexibility to continue investing in growth, innovation, and long-term value creation. Notably, during the second quarter, we generated adjusted net income of $63 million, and we believe we will maintain adjusted net income profitability for the second half of 2026. Now let's turn to our second quarter highlights. We had a strong second quarter at Legend as CARVYKTI continues to expand globally, maintaining its market leadership in CAR-T. Additionally, we recently presented compelling early efficacy and safety data from our in vivo CAR-T platform and plan to provide meaningful updates to these programs at future medical conferences.
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